1. For nonrodent studies, dose groups usually consist of at least 3 animals/sex/group, with an additional 2/sex/group for recovery, if appropriate (see Section 2.4).〔【出典】ICHガイドライン 〕
If he wish to perpetuate the difference, to form a breed with the peculiarity in question strongly marked, he selects such male and female individuals as exhibit the desired character, and breeds from them.〔【出典】日英対訳文・対応付けデータ(独立行政法人情報通信研究機構)〕"_DARWI", "2349129"
Information available from general toxicology studies on the pharmaceutical's effect on reproductive organs should be used as the basis of the assessment of impairment of fertility.〔【出典】ICHガイドライン 〕