(2) Where the provisions then in force remain applicable as prescribed in the preceding paragraph, with regard to the application of penal provisions to acts committed after the enforcement of a Municipal Ordinance on Green Space-Area Ratios, etc., the provisions then in force shall remain applicable.〔【出典】日本法令外国語訳データベースシステム 〕
These characteristics include container wall thickness, closure geometry, surface area to volume ratio, headspace to volume ratio, water vapour permeation rate or oxygen permeation rate per dosage unit or unit fill volume, as appropriate.〔【出典】ICHガイドライン 〕
In trials with a long time-scale for the accrual of subjects, the rate of accrual should be monitored and, if it falls appreciably below the projected level, the reasons should be identified and remedial actions taken in order to protect the power of the trial and alleviate concerns about selective entry and other aspects of quality.〔【出典】ICHガイドライン 〕