(3) Injections may be prepared as Freeze-dried Injections or Powders for Injections to prevent degradation or deactivation of the active substance(s) in solution.〔【出典】第十六改正日本薬局方(平成23年3月24日 厚生労働省告示第65号)〕
(2) The employer shall, in the case described in the preceding paragraph, and when having workers carry out work installing or removing an insulating device, have the worker engaging in the said work wear personal insulating protective equipment or have them use live line work instruments.〔【出典】日本法令外国語訳データベースシステム 〕
(2) The employer shall, as regards personal insulating protective equipment, live line work instruments and an insulating device listed in item (v) of the preceding paragraph, which are used for a charged circuit of 750 V or less for direct current or of 300 V for alternative current or less, use those having an insulating effect corresponding to the voltage of the said charged circuit.〔【出典】日本法令外国語訳データベースシステム 〕
(2) A worker shall, when having been instructed to use a live line work instrument or live line work equipment in the case set forth in the preceding paragraph, use it.〔【出典】日本法令外国語訳データベースシステム 〕
(2) A worker shall, in the work set forth in the preceding paragraph, when having been instructed to use live line work equipment by the employer, use it.〔【出典】日本法令外国語訳データベースシステム 〕
(2) A worker shall, in the work set forth in the preceding paragraph, when having been instructed to wear personal insulating protective equipment, install an insulating device, and use live line work instruments or live line work equipment by the employer, wear, install, or use them respectively.〔【出典】日本法令外国語訳データベースシステム 〕
(2) A worker shall, in the work set forth in the preceding paragraph, when having been instructed to wear personal insulating protective equipment or use live line work instruments by the employer, wear, or use them respectively.〔【出典】日本法令外国語訳データベースシステム 〕
(2) A worker shall, in the work set forth in the preceding paragraph, when having been instructed to wear protective equipment or use live line work instruments or live line work equipment by the employer, wear or use them respectively.〔【出典】日本法令外国語訳データベースシステム 〕
2.ウイルス感染性の不活化は、しばしば急速な初期相とそれに続く遅い相からなる2相性の曲線を示す。
2. Inactivation of virus infectivity frequently follows a biphasic curve in which a rapid initial phase is followed by a slower phase.〔【出典】ICHガイドライン 〕
In November and December 2003 IHCSA implemented English language training for the staff of non-governmental organizations (NGOs) in cooperation with the Japan NGO Center for International Cooperation (JANIC)."IC002004", "2357563"
(3) A worker shall, in the work set forth in the preceding two paragraphs, and when having been instructed to install an insulating device, wear personal insulating protective equipment, or use live line work instruments by the employer, install, wear, or use them respectively.〔【出典】日本法令外国語訳データベースシステム 〕
6. Addition of individual virus reduction factors resulting from similar inactivation mechanisms along the manufacturing process may overestimate overall viral clearance.〔【出典】ICHガイドライン 〕
a) Care should be taken in preparing the high-titer virus to avoid aggregation which may enhance physical removal and decrease inactivation thus distorting the correlation with actual production.〔【出典】ICHガイドライン 〕
f) Virus inactivation is time-dependent, therefore, the amount of time a spiked product remains in a particular buffer solution or on a particular chromatography column should reflect the conditions of the commercial-scale process.〔【出典】ICHガイドライン 〕
NAT will be an effective evaluation method for virus removal capability for viral clearance. However, in case of viral inactivation process, viral inactivation obtained by this method may be underrated, since there is a case that inactivated virus still shows positive on nucleic acid.〔【出典】第十六改正日本薬局方(平成23年3月24日 厚生労働省告示第65号)〕
pH is defined as the reciprocal of the common logarithm of hydrogen ion activity, which is the product of hydrogen ion concentration and the activity coefficient. Conventionally it is used as a scale of hydrogen ion concentration of a sample solution.〔【出典】第十六改正日本薬局方(平成23年3月24日 厚生労働省告示第65号)〕